Overview |
bs-18663R-Biotin |
MAP3K13 Polyclonal Antibody, Biotin Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Mouse |
Cow |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human MAP3K13 |
801-900/966 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
9175 |
O43283 |
Cytoplasm, Cell membrane |
Mitogen-activated protein kinase kinase kinase 13; MAP3K13; Leucine zipper-bearing kinase; Mixed lineage kinase; MLK; LZK |
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |