Overview |
bs-16957R-PE-Cy5.5 |
KHSRP Polyclonal Antibody, PE-Cy5.5 Conjugated |
WB |
Human |
Mouse, Rat, Dog, Pig, Horse |
Specifications |
PE-Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human KHSRP |
221-320/711 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
8570 |
Q92945 |
Cytoplasm, Nucleus |
Far upstream element-binding protein 2; KHSRP; FUSE-binding protein 2; KH type-splicing regulatory protein; KSRP; p75; FUBP2 |
Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs. |
Application Dilution |
WB |
1:300-5000 |