Overview |
bs-16263R-PE-Cy7 |
GPR75 Polyclonal Antibody, PE-Cy7 Conjugated |
WB |
Mouse |
Human |
Specifications |
PE-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human GPCR GPR75 |
151-250/540 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
10936 |
O95800 |
Cell membrane |
Probable G-protein coupled receptor 75; GPR75; |
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. |
Application Dilution |
WB |
1:300-5000 |