| Overview |
| bs-11898R-PE |
| NFIA/NF-1 Polyclonal Antibody, PE Conjugated |
| WB |
| Rat |
| Human, Mouse, Dog, Cow, Sheep, Pig, Chicken |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human NFIA/NF-1 |
| 41-140/509 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| Nucleus |
| CCAAT binding transcription factor; CCAAT Box Binding Transcription Factor; CCAAT-box-binding transcription factor; CTF; FLJ39164; NF I/A; NF-I/A; NF1 A; NF1-A; NF1A; NFI A; NFI L; NFI-A; NFIA; NFIA_HUMAN; Nuclear Factor 1 A; Nuclear factor 1 A type; Nuclear factor 1 A-type; Nuclear factor 1/A; Nuclear Factor 1A; Nuclear Factor I A; Nuclear factor I/A; nuclear factor I/X CCAAT-binding transcription factor; ynuclear factor I/X CCAAT-binding transcription factor; Nuclear factor I/X; Nuclear Factor IA; TGGCA binding protein; TGGCA-binding protein. |
| NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter. |
| Application Dilution |
| WB |
1:300-5000 |
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