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Angiopoietin 2 Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Pig
  • Chicken
Overview
Catalog # bs-0677R-HRP
Product Name Angiopoietin 2 Polyclonal Antibody, HRP Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Pig, Chicken
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Angiopoietin 2
Immunogen Range 401-496/496
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 285
Swiss Prot O15123
Subcellular location Secreted
Synonyms ANG2; AGPT2; Angiopoietin-2; ANG-2; ANGPT2
Background Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500