New to Bioss? Enjoy 35% of your first order. Use code "FirstOrder35" - Offer valid for new U.S. Customers on direct orders only

Cytochrome C Polyclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse
  • Rat
  • Chicken
  • Rabbit

Predicted Reactivity

  • Cow
  • Pig
  • Horse
  • Guinea Pig
Overview
Catalog # bs-0013R-PE
Product Name Cytochrome C Polyclonal Antibody, PE Conjugated
Applications WB, FCM
Reactivity Human, Mouse, Rat, Chicken, Rabbit
Predicted Reactivity Cow, Pig, Horse, Guinea Pig
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Cytochrome C
Immunogen Range 51-105/105
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 54205
Swiss Prot P99999
Subcellular location Cytoplasm, Cell membrane
Synonyms CYC; HCS; THC4; Cytochrome c; CYCS
Background Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Application Dilution
WB 1:500-2000
FCM 1:20-100