Overview |
bsm-51699M |
TSG101 Monoclonal Antibody |
WB |
Human |
Specifications |
Unconjugated |
Mouse |
Recombinant human TSG101. |
Monoclonal |
G6F4 |
0.5ug/ul |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
7251 |
Q99816 |
Cytoplasm, Nucleus, Cell membrane |
Tumor susceptibility gene 101 protein; ESCRT I complex subunit TSG101; ESCRT-I complex subunit TSG101; TSG 10; TSG 101; TSG10; Tumor susceptibility gene 10; Tumor susceptibility gene 101; Tumor susceptibility protein; Tumor susceptibility protein isoform 3; VPS 23; VPS23; TS101_HUMAN. |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. |
Application Dilution |
WB |
=1:500-2000, |