RCC1 Monoclonal Antibody
Applications
Predicted Reactivity
Overview | |
Catalog # | bsm-51500M |
Product Name | RCC1 Monoclonal Antibody |
Applications | WB |
Predicted Reactivity | Human, Mouse |
Specifications | |
Conjugation | Unconjugated |
Host | Mouse |
Source | Recombinant human RCC1. |
Clonality | Monoclonal |
Clone # | G14A2 |
Isotype | IgG1 |
Concentration | 0.5ug/ul |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 1104 |
Swiss Prot | P18754 |
Subcellular location | Cytoplasm, Nucleus |
Synonyms | Cell cycle regulatory protein; CHC 1; CHC1; Chromosome condensation 1; Chromosome condensation protein 1; Guanine nucleotide releasing protein; HERC2; Ran GEF; RanGEF; RCC 1; RCC1 I; Regulator of chromosome condensation 1; Regulator of chromosome condensation; SHEP1; RCC1_HUMAN. |
Background | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. |
Application Dilution | |
WB | =1:500-2000, |