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UNC 0224

Overview
Catalog # bs-83101c-1-mg
Product Name UNC 0224
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information UNC0224 is a potent inhibitor of histone methyltransferases G9a / EHMT2 (IC50 = 15 nM) and GLP / EHMT1 (IC50 ~ 39 nM) but not SET7/9 and SET8.1-3 Has been employed, as part of a small molecule cocktail, to reprogram somatic cells to pluripotent stem cells.4
Description CAS Number: 1197196-48-7

Chemical Name: 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine

Molecular weight: 485.68

Formula: C26H43N7O2

Solubility: DMSO (50 mg/ml)

Physical Properties: White to off-white solid

Purity: >98% by TLC NMR (Conforms)