Afatinib
Overview | |
Catalog # | bs-82885c-10-mg |
Product Name | Afatinib |
Specifications | |
Storage Buffer | Off-white solid |
Storage Condition | -20°C |
Target | |
Product Information | Afatinib is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50 = 0.5 nM) and HER2 (IC50 = 14 nM). |
Description | CAS Number: 850140-72-6 Chemical Name: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide Molecular weight: 485.94 Formula: C24H25ClFN5O3 Solubility: DMSO (>25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Pale yellow solid Purity: 99% by HPLC, NMR (Conforms) |