Amphotericin B

Overview
Catalog #	bs-82490c-1-g
Product Name	Amphotericin B
Specifications
Storage Buffer	Red solid
Storage Condition	-20°C / Protect from light
Target
Product Information	Amphotericin B is a powerful antimycotic, effective against a wide variety of fungi, including yeast, via two mechanisms: forming pores in the plasma membrane, leading to leakage and death1, and causing oxidative stress2. Other mechanisms have more recently been proposed, including formation of intracellular amphotericin B-containing vesicular bodies that target vacuoles3. Amphotericin B is also effective against some parasites, such as Leishmania spp4. Because of its potency and broad-spectrum activity, it is a common additive used to maintain sterility in cell culture and viral transport media.
Description	CAS Number: 1397-89-3 Chemical Name: Molecular weight: 924.08 Formula: C47H73NO17 Solubility: DMSO (18 mg/ml) Physical Properties: Yellow or orange solid Purity: 90% by HPLC NMR (Conforms)