Ansamitocin P3
Overview | |
Catalog # | bs-82432c-1-mg |
Product Name | Ansamitocin P3 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4. |
Description | CAS Number: 66547-09-9 Chemical Name: Molecular weight: 635.16 Formula: C32H43ClN2O9 Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml) Physical Properties: Yellow solid Purity: >90% by TLC [1:9 CH3OH:CH2Cl2, Rf = 0.54] remainder is P-1, P-2 and P-4. NMR (Conforms) |