Tunicamycin
Overview | |
Catalog # | bs-82395c-5-mg |
Product Name | Tunicamycin |
Specifications | |
Storage Buffer | Solution in DMSO |
Storage Condition | -20°C |
Target | |
Product Information | Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain. The structure shown above is for tunicamycin B (the C15 homolog) Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis1. Causes endoplasmic reticulum stress-induced autophagy2 and unfolded protein response3. Arrests cell cycle in late G14. |
Description | CAS Number: 11089-65-9 Chemical Name: Molecular weight: Avg 840.0 Formula: C38H62N4O16 (tun. B) Solubility: DMSO (40 mg/ml) Ethanol (5 mg/ml) Physical Properties: White solid Purity: 99% by TLC, NMR (Conforms) |