Stavudine
Overview | |
Catalog # | bs-82147c-200-mg |
Product Name | Stavudine |
Specifications | |
Storage Buffer | Yellow solid |
Storage Condition | -20°C |
Target | |
Product Information | Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs).1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages.4 |
Description | CAS Number: 3056-17-5 Chemical Name: 2’,3’-Didehydro-3’-deoxythymidine Molecular weight: 224.22 Formula: C10H12N2O4 Solubility: DMSO (20 mg/ml) Water (20 mg/ml) Physical Properties: White solid Purity: >98% by HPLC, NMR (conforms) |