Amphotericin B
Overview | |
Catalog # | bs-80512C |
Product Name | Amphotericin B |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C / protect from light |
Target | |
Product Information | Molecular Weight:924.1 Formula:C47H73NO17 Purity:>90% Solubility:Soluble in DMSO (up to 18 mg/ml), Chemical Name: |
Description | Amphotericin B is a powerful antimycotic, effective against a wide variety of fungi, including yeast, via two mechanisms: forming pores in the plasma membrane, leading to leakage and death1, and causing oxidative stress2. Other mechanisms have more recently been proposed, including formation of intracellular amphotericin B-containing vesicular bodies that target vacuoles3. Amphotericin B is also effective against some parasites, such as Leishmania spp4. Because of its potency and broad-spectrum activity, it is a common additive used to maintain sterility in cell culture and viral transport media. |