Ansamitocin P3
Overview | |
Catalog # | bs-80447C |
Product Name | Ansamitocin P3 |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:635.16 Formula:C32H43ClN2O9 Purity:>90% Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 30 mg/ml with warming). Chemical Name: |
Description | Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4. |