Tunicamycin
Overview | |
Catalog # | bs-80411C |
Product Name | Tunicamycin |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:Avg 840.0 Formula:C38H62N4O16 (tun. B) Purity:>98% Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming). Chemical Name: |
Description | Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain. Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis1. Causes endoplasmic reticulum stress-induced autophagy2 and unfolded protein response3. Arrests cell cycle in late G14. |