Trifluorothymidine
Overview | |
Catalog # | bs-80163C |
Product Name | Trifluorothymidine |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:296.20 Formula:C10H11F3N2O5 Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml) Chemical Name:2’-Deoxy-5-trifluoromethyluridine |
Description | An analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes.3 Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.4 |