Tropodithietic acid [TDA]
Overview | |
Catalog # | bs-75692c-1mg |
Product Name | Tropodithietic acid [TDA] |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
Target | |
Product Information | CAS Number: 750590-18-2 Molecular formula: C8H4O3S2 Molecular weight: 212.3 Purity: >98% (HPLC) Appearance: Orange solid. Solubility: Soluble in DMSO, methanol or acetone. InChiKey: BLFCMITWMARUSM-UHFFFAOYSA-N SMILES: OC(=O)C1=C2SSC2=CC=CC1=O |
Description | Antibiotic. Isomeric to thiotropocin. Antibacterial. Active against Gram-positive and Gram-negative bacteria. Antifungal and anti-nematodical. Shows antitumor activity. Cytotoxic against selected mammalian neuronal cell lines. Bacterial signal substance. Acts as potent membrane antiporter for protons in exchange for cytoplasmic cations (e. g. K+). TDA collapses the cellular proton motive force (PMF) by affecting the transmembrane proton gradient but not the membrane potential. |