Bafilomycin C1
Overview | |
Catalog # | bs-75674c-1mg |
Product Name | Bafilomycin C1 |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
Target | |
Product Information | CAS Number: 88979-61-7 Molecular formula: C39H60O12 Molecular weight: 720.9 Purity: >98% (HPLC) Appearance: Yellow powder. Solubility: Soluble in 100% ethanol, methanol, DMSO or dimethyl formamide. InChiKey: WUDBXVQNMOTFEE-WSNZTHDZSA-N SMILES: [H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C/[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)\C=C\C(O)=O)[C@H](C)[C@H](O1)C(C)C |
Description | Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, insecticidal and anthelmintic. Antifungal activity, especially against C. albicans. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. Cytotoxic activity against SMMC7721 HCC cells. Potential candidate for hepatic carcinoma chemotherapy. |