TG007
Overview | |
Catalog # | bs-75555c-5mg |
Product Name | TG007 |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
Target | |
Product Information | CAS Number: 719277-30-2 Molecular formula: C14H15NO3S Molecular weight: 277.3 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml). InChiKey: RLEOCVDWLAYGRX-AUWJEWJLSA-N SMILES: O=C(C)/C=C1SC2=CC=C(OC(C)=O)C=C2N\1CC |
Description | Cell permeable ATP-competitive DYRK1A and DYRK1B inhibitor. Inhibits phosphorylation of Tau-protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo. |