TCS PIM-1 1
Overview | |
Catalog # | bs-6447c-2mg-solid |
Product Name | TCS PIM-1 1 |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 367.2 Formula: C18 H11 Br N2 O2 CAS Number: 491871-58-0 InChi Key: SVSYJTYGPLVUOZ-UHFFFAOYSA-N InChi: InChI=1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23) Smiles: N#CC1C(=O)NC(=CC=1C1C=CC=CC=1)C1=CC(Br)=CC=C1O Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years |
Description | TCS PIM-1 1 (SC 204330) is a potent and selective inhibitor of ATP-competitive Pim-1 kianse with IC50 of 50 nM, shows good selectivity over Pim-2 and MEK1/MEK2 with IC50 > 20000 nM. |