TCID --- Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) Inhibitor
| Overview | |
| Catalog # | bs-60197c-2-mg-solid |
| Product Name | TCID --- Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) Inhibitor |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 283.92 Formula: C9 H2 Cl4 O2 CAS Number: 30675-13-9 InChi Key: IDLAOWFFKWRNHB-UHFFFAOYSA-N InChi: InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2 Smiles: O=C1CC(=O)C2C1=C(Cl)C(Cl)=C(Cl)C=2Cl Purity: 98.0 Solubility: DMSO up to 50 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | TCID is a novel potent and selective inhibitor of ubiquitin C-terminal hydrolase-L3 (UCH-L3) with an IC50 ~0.6 μM. It has ~125-fold greater selectivity over UCH-L1 (ubiquitin C-terminal hydrolase L1, IC50 ~75 μM). TCID can diminish glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons. |
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