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API5 Polyclonal Antibody, AbBy Fluor® 555 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Dog
  • Cow
  • Pig
  • Horse
  • Guinea Pig
Overview
Catalog # bs-1252R-BF555
Product Name API5 Polyclonal Antibody, AbBy Fluor® 555 Conjugated
Applications WB, FCM
Reactivity Mouse
Predicted Reactivity Human, Rat, Dog, Cow, Pig, Horse, Guinea Pig
Specifications
Conjugation AbBy Fluor® 555
Host Rabbit
Source KLH conjugated synthetic peptide derived from human API5
Immunogen Range 351-460/504
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8539
Swiss Prot Q9BZZ5
Subcellular location Cytoplasm, Nucleus
Synonyms AAC11; AAC-11; Apoptosis inhibitor 5; API-5; Antiapoptosis clone 11 protein; Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; FIF; Protein XAGL; API5; MIG8
Background Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Application Dilution
WB 1:300-5000
FCM 1:20-100