Dihexa
| Overview | |
| Catalog # | bs-6534C |
| Product Name | Dihexa |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 504.66 Formula: C27 H44 N4 O5 CAS Number: 1401708-83-5 InChi Key: XEUVNVNAVKZSPT-JTJYXVOQSA-N InChi: InChI=1S/C27H44N4O5/c1-4-6-8-12-24(34)30-22(18-20-13-15-21(32)16-14-20)26(35)31-25(19(3)5-2)27(36)29-17-10-7-9-11-23(28)33/h13-16,19,22,25,32H,4-12,17-18H2,1-3H3,(H2,28,33)(H,29,36)(H,30,34)(H,31,35)/t19-,22-,25-/m0/s1 Smiles: C[C@@H](CC)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)CCCCC)C(=O)NCCCCCC(N)=O Purity: 98.0 Solubility: DMSO (Slightly), Methanol (Slightly) Appearance: White to Off-White Solid Shelf Life: 1.0 years |
| Description | Dihexa, also known as PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. Dihexa has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor. |
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