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eIF4A1 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated

Applications

  • WB
  • FCM
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61878r-apc-cy5-100ul
Product Name eIF4A1 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated
Applications WB, FCM, IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation APC-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human eIF4A1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 1973
Swiss Prot P60842
Subcellular location Extracellular, Cytoplasm
Synonyms DDX2; DDX2A; eIF 4A I; EIF4A; eIF4A I; eIF4A-I; EIF4A1.
Background ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200