Overview |
bs-7865R-APC |
GPSM1 Polyclonal Antibody, APC Conjugated |
IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse, Rat, Sheep, Horse |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human GPSM1 |
201-300/675 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
26086 |
Cytoplasm, Cell membrane |
Activator of G-protein signaling 3;AGS3;AGS3 homolog;C10a;G protein signaling modulator 1 AGS3 like, C. elegans;G-protein-signaling modulator 1;GPSM1;GPSM1_HUMAN. |
Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. |
Application Dilution |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |