Overview |
bs-15548R-RBITC |
IFI16 Polyclonal Antibody, RBITC Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Mouse |
Human |
Specifications |
RBITC |
Rabbit |
KLH conjugated synthetic peptide derived from human IFI16 |
701-785/785 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3428 |
Q16666 |
Cytoplasm, Nucleus |
I16; Gamma interferon inducible protein 16; Gamma-interferon-inducible protein i16; IF16_HUMAN; i204; NGIP1; interferon activated gene 204; Interferon gamma induced protein I 16; Interferon gamma inducible protein 16; Interferon-inducible myeloid dferentiation transcriptional activator; p204; PYHIN2. |
IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |