Rabbit Anti-MICA Polyclonal Antibody


Catalog #

 bs-0832R

Size

100ul
$220.00

Antibody Type

Polyclonal

Host

Rabbit

Isotype

IgG

Reactivity

Human,

Concentration

1ug/uL

Application

WB, ELISA, IHC-P, IF

Background

The MHC class I chain-related (MIC) proteins are related to the Major histocompatibility complex (MHC) class I proteins which are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. The MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity. MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. MICA is present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.

Additional Information

Conjugation Unconjugated
Target Protein MICA
Gene ID Entrez Gene: 4276
Modification Site
Source KLH conjugated synthetic peptide derived from human MICA
Purification purified by Protein A and peptide affinity chromatography
Storage Condition Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months
Synonym MHC I a; MHC class I polypeptide-related sequence A; MHCA; MHC class-I chain related protein A; HLA class I antigen; FLJ36918; FLJ60820; MGC111087; MGC21250; MHC class I chain related gene A protein; MHC class I chain related protein A; MHC class I chain related protein A HLA B HLA C; MHC class I polypeptide related sequence A; MHC class I related protein; MIC A; PERB11.1; Stress inducible class I homolog; MICA_HUMAN; MIC A; MIC-A; micA.
Publication



bs-0832R
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MICA/MHC I a Polyclonal Antibody, Unconjugated (bs-0832R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

bs-0832R
Formalin-fixed and paraffin embedded mouse intestine labeled with Anti-MICA/MHC I a Polyclonal Antibody, Unconjugated (bs-0832R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

bs-0832R
Formalin-fixed and paraffin embedded mouse lung labeled with Anti-MICA/MHC I a Polyclonal Antibody, Unconjugated (bs-0832R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.


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