NLRP3 Recombinant Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-61254r-100uL |
| Product Name | NLRP3 Recombinant Antibody |
| Applications |
WB
|
| Reactivity | Mouse |
| Predicted Reactivity | Human, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | A synthesized peptide derived from human NLRP3 |
| Clonality | Recombinant |
| Clone # | 1F5 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 114548 |
| Swiss Prot | Q96P20 |
| Subcellular location | Cytoplasm |
| Synonyms | AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1; AII/AVP; Mmig1; NLRP3_HUMAN; NLRP3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1 (CLR1.1); Cold-induced autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; 3.6.4.-; NLRP3_MOUSE; Cold autoinflammatory syndrome 1 protein homolog; Mast cell maturation-associated-inducible protein 1; NLR family pyrin domain containing 3; cold autoinflammatory syndrome 1; deafness, autosomal dominant 34; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 |
| Background | Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis. |
| Application Dilution | |
| WB | 1:500-2000 |
Frequently asked questions
Which applications is NLRP3 Recombinant Antibody (bsm-61254R) validated for, and at what dilution?
bsm-61254R is validated for WB (1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NLRP3 Recombinant Antibody (bsm-61254R) react with?
Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat.
How should bsm-61254R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
What immunogen was used to raise NLRP3 Recombinant Antibody (bsm-61254R)?
A synthesized peptide derived from human NLRP3