Ki67 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-60738r |
| Product Name | Ki67 Recombinant Antibody |
| Applications | IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Ki67 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 4288 |
| Swiss Prot | P46013 |
| Subcellular location | Nucleus |
| Synonyms | Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; Ki67; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_HUMAN. |
| Background | Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation. |
| Application Dilution | |
| IHC-P | =1:200-800 |
| IHC-F | IHC-F=1:200-800 |
| IF | IF=1:200-800 |
| Flow-Cyt | Flow-Cyt=0.5ug/Test |
| ICC/IF | ICC/IF=1:200 |
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