CD11b Monoclonal Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54156r-apc-100uL |
| Product Name | CD11b Monoclonal Antibody, APC Conjugated |
| Applications |
WB
IF(IHC-P)
|
| Reactivity | Human |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | Recombinant Human ITGAM |
| Clonality | Monoclonal |
| Clone # | 9B3 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 3684 |
| Swiss Prot | P11215 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Antigen CD11b (p170); CD11 antigen like family member B; CD11 antigen like family member C; Cell surface glycoprotein MAC 1 subunit alpha; CR 3 alpha chain; CR3A; Integrin alpha M; Integrin alpha X; Integrin, alpha M (complement component 3 receptor 3 subunit); Integrin, alpha X (antigen CD11C (p150), alpha polypeptide); Integrin, alpha X (complement component 3 receptor 4 subunit); ITGAM; ITGAX; Leu M5, alpha subunit; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor MO1; Leukocyte adhesion receptor p150,95; Leukocyte surface antigen p150,95, alpha subunit; MAC1A; Macrophage antigen alpha polypeptide; MO1A; Myeloid membrane antigen, alpha subunit; Neutrophil adherence receptor alpha M subunit; p150 95 integrin alpha chain; SLEB6; ITAM_HUMAN; c equivalent; Integrin αM. |
| Background | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| Application Dilution | |
| WB | 1:1000-2000 |
| IF(IHC-P) | IFIHC-P1:200-800 |
Frequently asked questions
Which applications is CD11b Monoclonal Antibody, APC Conjugated (bsm-54156R-APC) validated for, and at what dilution?
bsm-54156R-APC is validated for WB(WB) (1:1000-2000); IF(IHC-P)(IF(IHC-P)) (1:200-800). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CD11b Monoclonal Antibody, APC Conjugated (bsm-54156R-APC) react with?
Tested reactivity: Human.
How should bsm-54156R-APC be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CD11b Monoclonal Antibody, APC Conjugated (bsm-54156R-APC)?
Recombinant Human ITGAM
What are the excitation and emission wavelengths of the APC conjugate (bsm-54156R-APC)?
APC on bsm-54156R-APC: excitation / emission 650nm/660nm.