MMP3 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54152r |
| Product Name | MMP3 Recombinant Antibody |
| Applications | WB, IHC-P |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein within C-terminal human MMP3 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 4314 |
| Swiss Prot | P08254 |
| Subcellular location | Secreted |
| Synonyms | Stromelysin-1; Matrix metalloproteinase-3; Transin-1; SL-1; MMP-3; MMP3; STR1; CHDS6; STMY1. |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, the progression of atherosclerosis, activation of procollagenase and tumor initiation. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
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