Overview |
bsm-52316R |
Bax (3C3) Monoclonal Antibody |
WB, FCM, IHC-P |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant human Bak between 20 to 150 amino acids |
Monoclonal |
3C3 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
581 |
Q07812 |
Cytoplasm, Mitochondrion, Membrane bound |
Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BCL2L4 |
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |