Overview |
bsm-52251R |
VDAC1 (9A7 ) Monoclonal Antibody |
WB, IHC-P, IHC, IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Human VDAC1 protein between 1 to 100 amino acids |
1-100/283 |
Monoclonal |
9A7 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
7416 |
P21796 |
Voltage-dependent anion-selective channel protein 1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC-1, hVDAC1 |
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC |
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IF |
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