RIPK3 Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51714m-100uL |
| Product Name | RIPK3 Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Recombinant human RIPK3. |
| Clonality | Monoclonal |
| Clone # | D11F6 |
| Concentration | Lot Dependent |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 11035 |
| Swiss Prot | Q9Y572 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Receptor interacting protein 3; Receptor interacting serine threonine kinase 3; Receptor interacting serine/threonine protein kinase 3; Receptor-interacting protein 3; Receptor-interacting serine/threonine-protein kinase 3; RIP 3; RIP like protein kinase 3; RIP-3; RIP-like protein kinase 3; RIPK 3; RIPK3_HUMAN. |
| Background | Essential for programmed necrosis in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. |
| Application Dilution | |
| WB | =1:500-1000 |
Frequently asked questions
Which applications is RIPK3 Monoclonal Antibody (bsm-51714M) validated for, and at what dilution?
bsm-51714M is validated for WB (WB=1:500-1000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does RIPK3 Monoclonal Antibody (bsm-51714M) react with?
Tested reactivity: Human.
How should bsm-51714M be stored?
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise RIPK3 Monoclonal Antibody (bsm-51714M)?
Recombinant human RIPK3.