Overview |
bsm-51281M |
CDKN1B (10B7) Monoclonal Antibody |
WB, IHC-P |
Human |
Specifications |
Unconjugated |
Mouse |
This CDKN1B antibody is generated from a mouse immunized with CDKN1B recombinant protein. |
Monoclonal |
10B7 |
IgG1 |
0.5ug/ul |
Purified by Protein G. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
1027 |
P46527 |
KIP1; MEN4; CDKN4; MEN1B; P27KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; CDKN1B |
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |