NFKB p65 (Acetyl-Lys314/Lys315) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-33387M-100uL |
| Product Name | NFKB p65 (Acetyl-Lys314/Lys315) Monoclonal Antibody |
| Applications |
IHC-F
IF
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | KLH conjugated Synthesised phosphopeptide derived from human NFKBp65 around the acetylation site of Lys314/315 |
| Clonality | Monoclonal |
| Clone # | 4B11 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 5970 |
| Swiss Prot | Q04206 |
| Synonyms | NF-kB p65 (Acetyl K314/K315); Acetyl-NF-kB p65 (K314/K315); NFkB-p65(Acetyl K314/K315); RELA(Acetyl K314/K315); NF kB P65; NF-kB p65; NFKBp65; NF-_Bp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription Factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)); V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A; p65NFKB; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NFKB 3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells. |
| Background | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]. |
| Application Dilution | |
| IHC-F | 1:100-500 |
| IF | 1:100-500 |
| IHC-P | 1:100-500 |
Frequently asked questions
Which applications is NFKB p65 (Acetyl-Lys314/Lys315) Monoclonal Antibody (bsm-33387M) validated for, and at what dilution?
bsm-33387M is validated for IHC-F (1:100-500); IF (1:100-500); IHC-P (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NFKB p65 (Acetyl-Lys314/Lys315) Monoclonal Antibody (bsm-33387M) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-33387M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NFKB p65 (Acetyl-Lys314/Lys315) Monoclonal Antibody (bsm-33387M)?
KLH conjugated Synthesised phosphopeptide derived from human NFKBp65 around the acetylation site of Lys314/315