RNF98 Polyclonal Antibody

Applications

ELISA
IHC-P
IHC-F
IF

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bs-9155R
Product Name	RNF98 Polyclonal Antibody
Applications	ELISA, IHC-P, IHC-F, IF
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human TRIM36/RNF98
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	55521
Synonyms	Acrosome RBCC protein; E3 ubiquitin protein ligase TRIM36; E3 ubiquitin-protein ligase Trim36; Haprin; RBCC728; Ring finger protein 98; TRI36_HUMAN; TRIM 36; TRIM36; Tripartite mot containing 36; Tripartite mot containing protein 36; Tripartite mot protein 36; Tripartite mot-containing protein 36; Zinc binding protein Rbcc728; Zinc-binding protein Rbcc728.
Background	TRIM36 (tripartite motif-containing 36), also known as RNF98 (RING finger protein 98), HAPRIN (haploid germ cell-specific RBCC protein) or RBCC728, is a 728 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. Predominantly expressed in prostate, testis and brain with weak expression in heart, kidney and lung, TRIM36 contains two B box-type zinc fingers, a SPRY domain, a coiled-coil domain, a fibronectin type-III domain and a RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. Localizing to the cytoplasm and the acrosomal region of germ cells and mature sperm, TRIM36 is believed to play a role in the acrosome reaction and fertilization. In addition, TRIM36 is overexpressed in prostate cancer, suggesting a possible role for TRIM36 in prostate tumorigenesis.
Application Dilution
ELISA	WB1:300-5000
IHC-P	1:200-400
IHC-F	IFIHC-P1:50-200
IF