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Mouse ox-LDL

Applications

  • Others
Overview
Catalog # bs-8574p-10mg
Product Name Mouse ox-LDL
Applications Others
Specifications
Conjugation Unconjugated
Source Purified native protein
Storage Buffer 10 mM PBS(pH=7.4) with 0.01 μM EDTA
Storage Condition Store at 2-8C for one year. Avoid repeated freeze/thaw cycles.
Target
Background

Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.