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25-Hydroxycholesterol

Overview
Catalog # bs-82905c-5mg
Product Name 25-Hydroxycholesterol
Specifications
Storage Buffer White or pale yellow solid
Storage Condition -20°C
Target
Product Information Metabolite resulting from the action of cholesterol 25-hydroxylase on cholesterol. However, since cholesterol 25-hydroxylase knock-out mice still have significant levels of 25-hydroxycholesterol there must be alternate pathways of generation that have yet to be determined.1 Likewise, the biological role of 25-hydroxycholesterol remains somewhat unclear. 25-Hydroxycholesterol is frequently mentioned as an important regulator of cholesterol metabolism, but apparently normal cholesterol regulation in organisms with both high and low levels of the compound make this association unclear. More recent reports have linked 25-hydroxycholesterol and one of it’s metabolites to immunoregulatory roles2, but more information is needed before it’s clear if that is indeed a primary role for the compound.
Description CAS Number: 2140-46-7

Chemical Name: 5-Cholesten-3β, 25-diol

Molecular weight: 402.66

Formula: C27H46O2

Solubility: DMSO or Ethanol

Physical Properties: White or pale yellow solid

Purity: 98% by TLC, NMR (Conforms)

Frequently asked questions

Which applications is 25-Hydroxycholesterol (bs-82905C) validated for, and at what dilution?

bs-82905C is validated for Life Science( N/A).

How should bs-82905C be stored?

-20°C Storage buffer: White or pale yellow solid

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