Mirabegron
| Overview | |
| Catalog # | bs-82828c-10mg |
| Product Name | Mirabegron |
| Specifications | |
| Storage Buffer | Beige solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Mirabegron is a potent (EC50 = 22.4 nM CHO cells expressing human ß3-ARs) beta-3 adrenergic receptor (ß3-AR) agonist with high selectivity over the beta-1 and beta-2 receptors.1 Clinically useful for the treatment of overactive bladder syndrome. Chronic treatment of human subjects with mirabegron increased brown adipose tissue (BAT) metabolic activity, increased HDL and bile acid levels, and produced substantial improvements in glucose and insulin metabolism.2 Mirabegron inhibited tumor growth in various tumor models including pancreatic ductal adenocarcinoma and hepatocellular carcinoma via altering global metabolism in an uncoupling protein 1 (UCP1; a key protein for non-shivering thermogenesis) dependent manner.3 |
| Description | CAS Number: 223673-61-8 Chemical Name: 2-(2-Amino-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]acetamide Molecular weight: 396.51 Formula: C21H24N4O2S Solubility: DMSO (40 mg/ml) Physical Properties: Beige solid Purity: >98% by HPLC NMR (Conforms) |
Frequently asked questions
Which applications is Mirabegron (bs-82828C) validated for, and at what dilution?
bs-82828C is validated for Life Science( N/A).
How should bs-82828C be stored?
-20°C Storage buffer: Beige solid