ABT-263
| Overview | |
| Catalog # | bs-82647c-5mg |
| Product Name | ABT-263 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A useful tool compound which has shown interesting results in various cancer clinical trials2. Synergizes with deoxyglucose and other agents, inducing apoptosis in cancer cells in a xenograft mouse model3. A novel senolytic agent, inducing apoptosis preferentially in senescent cells in a cell type-restricted manner4. |
| Description | CAS Number: 923564-51-6 Chemical Name: 4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)- 3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]-phenyl]sulfonyl]-benzamide Molecular weight: 974.6 Formula: C47H55ClF3N5O6S3 Solubility: DMSO (25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC (NMR Conforms) |
Frequently asked questions
Which applications is ABT-263 (bs-82647C) validated for, and at what dilution?
bs-82647C is validated for Life Science( N/A).
How should bs-82647C be stored?
-20°C Storage buffer: White solid