FOXL2 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-6633r |
| Product Name | FOXL2 Polyclonal Antibody |
| Applications |
WB
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse, Rat, Bovine |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human FOXL2 |
| Immunogen Range | 70-120/376 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 668 |
| Subcellular location | Nucleus |
| Synonyms | blepharophimosis; Blepharophimosis epicanthus inversus and ptosis 1; Blepharophimosis epicanthus inversus and ptosis; BPES 1; BPES; BPES1; epicanthus inversus and ptosis 1; forkhead box L2; Forkhead box protein L2; forkhead transcription factor FOXL2; FOX L2; FOXL 2; FOXL2; FOXL2_HUMAN; PFRK; PINTO; POF 3; POF3. |
| Background | Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. |
| Application Dilution | |
| WB | |
| IHC-P | |
| IHC-F | |
| IF | |
Frequently asked questions
Which applications is FOXL2 Polyclonal Antibody (bs-6633R) validated for, and at what dilution?
bs-6633R is validated for WB, IHC-P, IHC-F, IF.
Which species does FOXL2 Polyclonal Antibody (bs-6633R) react with?
Tested reactivity: Human, Mouse, Rat, Bovine.
How should bs-6633R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FOXL2 Polyclonal Antibody (bs-6633R)?
KLH conjugated synthetic peptide derived from human FOXL2 Immunogen range: 70-120/376.