Recombinant Human ACE2 Protein
Applications
Reactivity
| Overview | |
| Catalog # | bs-46110p-100ug |
| Product Name | Recombinant Human ACE2 Protein |
| Applications |
WB
ELISA
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant Human ACE2 Protein protein is expressed in Mammalian cells with C-His. It contains the amino acid sequence of Met1-Ser740. |
| Storage Buffer | Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | NP_001358344.1 |
| Swiss Prot | Q9BYF1 |
| Background | Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, and heart, in the colon, small intestine, and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor, don’t inhibit ACE-2 activity. ACE-2 may play an essential role in regulating heart function. |