Recombinant SARS-CoV-2 Spike protein fragment 2
Applications
Reactivity
| Overview | |
| Catalog # | bs-46108p-100ug |
| Product Name | Recombinant SARS-CoV-2 Spike protein fragment 2 |
| Applications |
WB
ELISA
|
| Reactivity | SARS-CoV-2 |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant SARS-CoV-2 Spike protein fragment 2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of Tyr1047-Gln1201. |
| Storage Buffer | Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | QHD43416.1 |
| Background | Protein S (PROS1) is a glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor-binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Frequently asked questions
Which applications is Recombinant SARS-CoV-2 Spike protein fragment 2 (bs-46108P) validated for, and at what dilution?
bs-46108P is validated for WB, ELISA.
Which species does Recombinant SARS-CoV-2 Spike protein fragment 2 (bs-46108P) react with?
Tested reactivity: SARS-CoV-2.
How should bs-46108P be stored?
The product should be stored at -70°C or -20°C. Storage buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
How is Recombinant SARS-CoV-2 Spike protein fragment 2 (bs-46108P) produced?
Recombinant SARS-CoV-2 Spike protein fragment 2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of Tyr1047-Gln1201.