IREB2 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-4484r-100uL |
| Product Name | IREB2 Polyclonal Antibody |
| Applications |
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IREB2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 3658 |
| Swiss Prot | P48200 |
| Synonyms | IRP 2; IRP-2; IRP2; ACO3; FLJ23381; IRE BP2; IRE-BP 2; IREB 2; IREB2; IREB2_HUMAN; iron regulatory protein 2; iron responsive element binding protein 2; Iron-responsive element-binding protein 2; irp2; IRP2AD; OTTHUMP00000185022. |
| Background | RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. |
| Application Dilution | |
| IHC-P | =1:100-500 |
| IHC-F | IHC-F=1:100-500 |
| IF | IF=1:100-500 |
Frequently asked questions
Which applications is IREB2 Polyclonal Antibody (bs-4484R) validated for, and at what dilution?
bs-4484R is validated for IHC-P (IHC-P=1:100-500); IHC-F (IHC-F=1:100-500); IF (IF=1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does IREB2 Polyclonal Antibody (bs-4484R) react with?
Tested reactivity: Human, Mouse.
How should bs-4484R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise IREB2 Polyclonal Antibody (bs-4484R)?
KLH conjugated synthetic peptide derived from human IREB2