| Overview |
| bs-43141p-100ug |
| Recombinant human CEACAM5 protein, C-His (HEK293) |
| Others |
| Others |
| Specifications |
| Unconjugated |
| Recombinant human CEACAM5 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 35-685/702 |
| 0.01M TBS(pH7.4) |
| The product should be stored at -70°C or -20°C. |
| Target |
| 1048 |
| P06731 |
| CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. |
Powered by Bioz