| Overview |
| bs-41494p-100ug |
| Recombinant SARS-COV-2 N Protein (Omicron, B.1.1.529) N-His |
| ELISA |
| Others |
| Specifications |
| Unconjugated |
| Recombinant SARS-COV-2 N Protein (Omicron, B.1.1.529) N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 1-419/419. |
| 0.01M TBS(pH7.4) |
| The product should be stored at -70°C or -20°C. |
| Target |
| 43740575 |
| P0DTC9 |
| Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |