Recombinan human ACE2 Protein, N-His

Overview
Catalog #	bs-41410p-1mg
Product Name	Recombinan human ACE2 Protein, N-His
Applications	WB, ELISA
Reactivity	Human
Specifications
Conjugation	Unconjugated
Source	Recombinan human ACE2 Protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 18-615aa.
Storage Buffer	Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	NP_001358344.1
Background	Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the outer surface (cell membranes) of cells in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II (a vasoconstrictor peptide) into angiotensin (1‚Äì7) (a vasodilator). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7) making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses including Severe acute respiratory syndrome coronavirus 2.